CD63 antilichaam

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.

CD63 antigen|Granulophysin|Lysosomal-associated membrane protein 3 (LAMP-3) |Lysosome integral membrane protein 1 (Limp1) |Melanoma-associated antigen ME491|OMA81H|Ocular melanoma-associated antigen|Tetraspanin-30 (Tspan-30) |CD63|MLA1|TSPAN30

967

P08962

Human

CD63 molecule

CD63

Cancer, Immunology, Cardiovascular, Signal Transduction

Protein A+G purified

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

≥95% as determined by SDS-PAGE

Liquid

35 kDa

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

5J7

ELISA, IHC, WB