CD68 Antilichaam

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

968

P34810

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 22-319 of human CD68 (NP_001242.2) .

Unconjugated

Primary Antibodies

Immunology

Affinity purification

Mouse fat

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 85kDa

IgG

WB: 1:500 - 1:2000

CD68

Mouse skin

Rat skin

CD68 molecule

Homo sapiens

Macrosialin, Gp110, CD68, CD68

WB

Liquid