CD69 Antilichaam (FN50] (PE)

The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) . It is expressed as a disulfide-linked dimer on B cells, T cells, NK cells, platelets, eosinophils, and neutrophils. It increases in expression upon cell activation and seems to serve a role as a signaling receptor.

969

Q07108

Human

FN50

PE

Primary Antibodies

Immunology

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The FN50 monoclonal antibody specifically reacts with human CD69, the 27-33 kDA type II transmembrane protein also known as the very early activation antigen (VEA) or the activation inducer molecule (AIM) .

CD69

CD69 molecule

Homo sapiens

Marzio, R., Jirillo, E., Ransijn, A., Mauel, J., Corradin, S. B. (1997) . Expression and function of the early activation antigen CD69 in murine macrophages.Journal of leukocyte biology,62 (3), 349-355.

Yokoyama, W. M., Koning, F., Kehn, P. J., Pereira, G. M., Stingl, G., Coligan, J. E., Shevach, E. M. (1988) . Characterization of a cell surface-expressed disulfide-linked dimer involved in murine T cell activation.The Journal of Immunology,141 (2), 369-376.

Sobel, E. S., Yokoyama, W. M., Shevach, E. M., Eisenberg, R. A., Cohen, P. L. (1993) . Aberrant expression of the very early activation antigen on MRL/Mp-lpr/lpr lymphocytes.The Journal of Immunology,150 (2), 673-682.

AIM, EA1, MLR-3, CLEC2C, GP32/28, BL-AC/P26, CD69

Flow

Liquid