CD72.1 Antilichaam [10,1.D2] (FITC)

Murine CD72.1 (Lyb-2.1), a type II integral membrane glycoprotein and a member of the C-lectin family of cell surface receptors, is a differentiation antigen of B cells and is found in mouse strains expressing the Lyb-2.1 allotype. CD72.1 is the ligand of CD5 which is distributed on all T cells and a small number of B cells. The 10.1.D2 monoclonal antibody blocks binding of CD5 to CD72 on the B cell surface which leads to inhibition of the positive signal resulting from CD5/CD72 pairing. However, 10.1.D2 can itself trigger a positive signal by binding CD72.

12517

P21855

P21855

Mouse

DBA/2 mouse spleen cells

[10.1.D2]

FITC

Primary Antibodies

Immunology, Signal Transduction

0.5 mg/mL

Supplied in PBS/NaN3

None

Blue Ice

Store vial at 2-8˚ C

IgG2b

CD72.1

CD72.1 Antibody [10.1.D2] for use in flow cytometry assays.

Cd72

CD72 antigen

Mus musculus

Lyb-2.1, CD72a, Lyb-2a

WB, IHC-Fr, ICC, Flow, Blocking, IP

Liquid