CD8 Antilichaam [RAVB3]

CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine-protein kinase p56lck.

925

P01732

P01732

Human

Ni-NTA purified recombinant human CD8 expressed in E. Coli strain BL21 (DE3) .

RAVB3

Unconjugated

Primary Antibodies

Immunology

Antibody is purified by protein A affinity chromatography.

Batch dependent

Purified antibody in PBS containing 0.03% sodium azide.

None

Blue Ice

CD8 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

CD8A

CD8a molecule

Homo sapiens

Veillette, A. et al. 1988. Cell 55:301.

MALCD8, MAL, p32, Leu2

ELISA, WB

116035