CD81 Antilichaam [2F7]

CD81, also known as TAPA-1, is an integral membrane protein expressed on a variety of cell types and has a high degree of sequence homology between human and mouse. CD81 is expressed on thymic stromal cells where it plays an important role in the transition of gammadelta+ T cells to more mature T cells with alphabeta T cell receptors. Immunohistochemical staining has revealed that its expression is localized to the subcapsular region of the thymus and, specifically, on cells that have distinct clustering patterns. It has been speculated that the ligand for CD81 is the pre-T cell receptor which is composed of a TCR beta chain and glycoprotein pTalpha. The monoclonal antibody 2F7 can block thymocyte interaction with CD81 in vitro.

12520

P35762

P35762

Mouse

Mouse epithelial cell line PAM212

[2F7]

Unconjugated

Primary Antibodies

Immunology

0.5 mg/mL

Supplied in PBS

None

Dry Ice

Store vial at -20˚ C

IgG

CD81

CD81 Antibody [2F7] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, costimulation, and blocking assays.

Cd81

CD81 antigen

Mus musculus

TAPA-1

IHC-Fr, Flow

Liquid