CD86 Antilichaam [24F] (FITC)

The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells. CD86 is a ligand for CD28 and CD152 and plays an essential role in B cell-T cell costimulatory interactions. The 24F antibody is capable of blocking the co-stimulatory activity of CD86.

56822

Rat

24F

FITC

Primary Antibodies

Innate Immunity

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Batch dependent

Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

None

Blue Ice

The product should be stored undiluted at 4˚ C and should be protected from prolonged exposure to light. Do not freeze.

Mouse IgG1, kappa

The 24F monoclonal antibody specifically reacts with CD86 (B7-2), a 90 kDA surface receptor present on antigen presenting cells and activated B and T cells.

Cd86

CD86 molecule

Rattus norvegicus

Maeda, K., Sato, T., Azuma, M., Yagita, H., Okumura, K. (1997) . Characterization of rat CD80 and CD86 by molecular cloning and mAb.International immunology,9 (7), 993-1000.

Damoiseaux, J. G., Yagita, H., Okumura, K., van Breda Vriesman, P. J. (1998) . Costimulatory molecules CD80 and CD86 in the rat

Tissue distribution and expression by antigen-presenting cells.Journal of leukocyte biology,64 (6), 803-809.

BLUESTONE, J. (1995) . New perspectives of CD28-B7-mediated T cell costimulation.Immunity,2, 555-559.

B7-2, Cd86

Flow

Liquid