CD8a Antilichaam [3-298] (FITC)

In the chicken the CD8 molecule is present in two forms - (i) a homodimer of two alpha chains and (ii) a heterodimer of an alpha chain and a beta chain. Chicken CD8 is expressed on approximately 80% of thymocytes, 45% of blood mononuclear cells, and 50% of spleen cells but less than 1% of cells in the bursa and bone marrow. While the vast majority of CD8+ cells in the thymus, spleen, and blood of adult chickens express both CD8alpha- and CD8beta-chains, a relatively large proportion of the CD8+ TCRgammadelta cells in the spleens of embryos and young chicks express only the alpha-chain of CD8. Among intestinal epithelial lymphocytes, the major CD8+ T cell populations present in mice are conserved but there is a population of TCRgammadelta CD8alphabeta cells in the chicken that is not found in rodents. The monoclonal antibody 3-298 recognizes the CD8alpha chain of both the chicken and turkey.

403158

Chicken, Turkey

Chicken thymocytes

[3-298]

FITC

Primary Antibodies

Cancer, Immunology, Signal Transduction

0.5 mg/mL

Supplied in PBS/NaN3

None

Blue Ice

Store vial at 2-8˚ C

IgG2b

CD8alpha

CD8a Antibody [3-298] for use in flow cytometry, immunohistochemistry, and western blotting assays.

CD8A

CD8a molecule

Gallus gallus

IHC, ICC, Flow, Blocking, IP, Costimulation

Liquid