CD8A Antilichaam - middengebied: Biotine (ARP59114 P050-Biotine)

CD8a molecule

CD8, p32, Leu2

925

P01732

NP_001139345

Human, Dog

The immunogen is a synthetic peptide directed towards the middle region of human CD8A

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.

CACYBP; UBC; CDK1; LNX2; LNX1; SREK1; LAT; SRSF1; CD8A; CD3D; CD8B; LCK; PTPRC; LGALS1; HLA-E; HLA-G; HLA-C; HLA-B; HLA-A; B2M; CD59

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Dog: 79%; Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

24kDa

Wet Ice

235

CD8A

CD8A

Rabbit

T-cell surface glycoprotein CD8 alpha chain

NM_001145873

GKRLGDTFVLTLSDFRRENEGYYFCSALSNSIMYFSHFVPVFLPAKPTTT