CD9 Antilichaam

CD9 Antibody: CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Like other tetraspanins, CD9 is a cell surface glycoproteins play a role in many cellular processes including differentiation, adhesion, and signal transduction (1) . CD9 expression plays a critical role in the suppression of cancer cell motility and metastasis. In one study, the knockdown of CD9 expression suppressed the metastatic capacity of human breast cancer cells (2), while other results have shown the opposite effect, suggesting that different proteins associated with CD9 account for its abilities to promote or suppress metastasis (3) .

928

P21926

NP_001760

Human

CD9 antibody was raised against a peptide corresponding to 19 amino acids near the center of human CD9.

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

CD9 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1384 - Human Uterus Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Cat: (90%), Bovine: (89%), Mouse: (84%), Rat: (84%), Boar: (78%)

CD9 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CD9 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

CD9

CD9

Homo sapiens

Murayama Y, Oritani K, and Tsutsui S. Novel CD9-targeted therapies in gastric cancer. World J. Gastroenterol. 2015; 21:3206-13.

Rappa G, Green TM, Karbanova J, Corbeil D, et al. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget 2015; 6:7970-91.

Zoller M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat. Rev. Cancer 2009; 9:40-55.

CD9 Antibody: CD9 molecule, MIC3, MRP-1, BTCC-1, DRAP-27, TSPAN29, TSPAN-29

ELISA, WB

4502693

Liquid