CD94 Antilichaam [18d3] (FITC)

The monoclonal antibody 18d3 reacts with the mouse CD94 receptor subunit, a type II transmembrane glycoprotein. CD94 is expressed on the surface of NK cells, NK T cells, and some memory phenotype CD8+ cells. When CD94 is paired with NKG2A, C, or E subunit, it binds the nonclassical MHC class Ib molecule Qa-1b and results in a CD94high population by flow cytometry. Approximately half of NK cells do not express NKG2A, C or E; these cells express CD94 on the surface in a form that does not bind Qa-1b and is believed to be nonfunctional, producing a CD94low population by flow cytometry. CD94 is thought to play a role in the adhesion and activation of the NK cell lineage.

16643

O54707

O54707

Mouse

CHO cells transfected with the B6 allele of CD94

[18d3]

FITC

Primary Antibodies

Immunology

0.5 mg/mL

Supplied in PBS/NaN3

None

Blue Ice

Store vial at 2-8˚ C

IgG2a

CD94

CD94 Antibody [18d3] for use in flow cytometry assays.

Klrd1

Killer cell lectin-like receptor, subfamily D, member 1

Mus musculus

Kp43, KLRD1

IHC-Fr, Flow

Liquid