Cdc25A (fosfo Ser76) Antilichaam

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

993

P30304

NP_001780.2

Human, Mouse, Rat

Cdc25A (Phospho-Ser76) antibody was raised against a peptide sequence around phosphorylation site of serine 76 (M-G-S (p) -S-E) derived from Human cdc25A.

Unconjugated

Primary Antibodies

Phospho-Specific, Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

70 kDa

This antibody detects endogenous level of cdc25A only when phosphorylated at serine 76.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

CDC25A

Cell division cycle 25A

Homo sapiens

Jin J, et al. (2003) Genes 17 (24) : 3062-74. Shimuta K, et al. (2002) EMBO J 21 (14) : 3694-703.

CDC25A2, MEK1, PRKMK1, CDC25M3, MPIP1

WB, IHC

42490758

Liquid