CDC25B Mouse Monoclonal Antibody [Kloon ID: LBI11C5]

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

Carrier-free (BSA/glycerol-free) CDC25B mouse monoclonal antibody, clone LBI11C5

Cell division cycle 25 homolog B (S. pombe) ; cell division cycle 25B; OTTHUMP00000030137; OTTHUMP00000030138; OTTHUMP00000030139

Homo sapiens cell division cycle 25B (CDC25B), transcript variant 2, mRNA.

994

P30305

Unconjugated

Cell cycle, MAPK signaling pathway, Progesterone-mediated oocyte maturation

Cell cycle, MAPK signaling pathway, Progesterone-mediated oocyte maturation

WB 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Phosphatase

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CDC25B

https://www.ncbi.nlm.nih.gov/gene/?term=994

https://www.uniprot.org/uniprot/P30305