CDC25C Antilichaam

This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq].

Western blot: 1:1000-1:8000

P30307

Human

This CDC25C antibody was produced from mouse immunized with CDC25C recombinant protein.

233CT9.6.6

WB, ELISA

Ascites

Ascites

This CDC25C antibody is available for research use only.

Aliquot the CDC25C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In ascites with 0.09% sodium azide

Titration of the CDC25C antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Western blot analysis of CDC25C antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (2) with the CDC25C gene. Expected molecular weight: ~53/60 kDa (unmodified/phosphorylated) .