CDC73 Antilichaam

CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.

Western blot: 1:1000-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25

Q6P1J9

Human

A portion of amino acids 132-161 from the human protein were used as the immunogen for the CDC73 antibody.

WB, IHC-P, FACS, IF

Antigen affinity purified

Purified

This CDC73 antibody is available for research use only.

Aliquot the CDC73 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

In 1X PBS, pH 7.4, with 0.09% sodium azide

The stated application concentrations are suggested starting points. Titration of the CDC73 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Nuclear

Western blot testing of human 1) 293T and 2) TT cell lysate with CDC73 antibody. Predicted molecular weight ~61 kDa.