CDH12 Polyklonale Antilichaam, PE-vervoeging

The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morpho-genesis (1-4) . Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity (5,6) . The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin b, to regulate cadherin function (7) . BR-cadherin (for brain-cadherin, also designated cadherin-12 or N-cadherin 2) is expressed specifically in neurons in the central nervous system and is thought to be involved in neuronal development (8) .

Br cadherin; BR-cadherin; Brain cadherin; CAD12_HUMAN; cadherin 12 N cadherin 2; Cadherin 12; Cadherin 12 precursor; Cadherin 12 type 2 N cadherin 2; Cadherin 12 type 2; Cadherin neural type 2; Cadherin-12; CDH12; CDHB; FLJ34857; N cadherin 2; N-cadherin 2; Neural type cadherin 2; Neuronal cadherin 2.

Cell membrane

Rat

291-390/794

CDH12

PE

KLH conjugated synthetic peptide derived from human CDH12

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

496,564nm/578nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit