CDK1 Antilichaam

The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

983

P06493

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-297 of human CDK1 (NP_001777.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 34kDa

IgG

CDK1

HeLa

Jurkat

Cyclin-dependent kinase 1

Homo sapiens

CDC2, CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2

WB, IHC

Liquid