CDK9 Antilichaam

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

1025

P50750

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 153-372 of human CDK9 (NP_001252.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Immunology, Signal Transduction

Affinity purification

A549

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 40kDa

IgG

CDK9

HeLa

U-251MG

Raji

BT-474

Mouse spleen

Cyclin-dependent kinase 9

Homo sapiens

CDK9, RP11-228B15.5, C-2k, CDC2L4, PITALRE, TAK, CTK1

WB, IHC, IF, IP

Liquid