CDX-3379
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
CDX-3379 is a humanized monoclonal antibody inhibitor targeting ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby inhibiting the phosphorylation of ErbB3. CDX-3379 can inhibit the growth and proliferation of tumor cells. CDX-3379 is promising for research of tumors expressing ErbB3 and NRG1, such as HNSCC[1].
12352203
EGFR
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Cancer-Kinase/protease
Cancer
[1]Duvvuri U, et al. Molecular and Clinical Activity of CDX-3379, an Anti-ErbB3 Monoclonal Antibody, in Head and Neck Squamous Cell Carcinoma Patients. Clin Cancer Res. 2019 Oct 1;25 (19) :5752-5758.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991240/
Inhibitory Antibodies
Phase 2
ErbB3/HER3
Beschrijving
CDX-3379 is a humanized monoclonal antibody inhibitor targeting ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby
Specificaties
Recent bekeken producten
SCD polyclonal antibody
GTR18043932-01
50 μL
(KO Validated) SUMO1 Polyclonal Antibody
E-AB-92410-01
60 µL
Salicylate hydroxylase, Microorganism
HY-E70520-01
1 KU
Purified Diphtheria Toxoid protein (cGMP/USP, vaccine grade, ~1500-2500 Lf/ml; Low endotoxin)
DTOX16-N-500
500 µg
BioCoupler® Glass Set (16 oz) x12
BCS1612
12 Each
BioCoupler® x 48
BC48
48 Each
BioTilt™ 25 (BT25)
BT25
25 Bundles
Purified Diphtheria Toxoid protein (antigen grade)
DTOX15-N-500
100 µg
Recent gezochte producten
SMRCD Polyclonal Antibody
JOT-AP14328-01
20 µL
MYCD Polyclonal Antibody
JOT-AP11603-01
20 µL
Anti-DCD Polyclonal Antibody
HX130014-01
50 µg
Anti-MYOCD Polyclonal Antibody
HV334024-01
50 µg
Anti-Human FTCD Polyclonal Antibody
HF652014-01
50 µg
Anti-Human PIK3CD Polyclonal Antibody
HT068014-01
50 µg
Anti-Human PRCD Polyclonal Antibody
HD164014-01
50 µg
SCD polyclonal antibody
GTR18043932-01
50 μL