CEACAM5 Antilichaam

CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2) . CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2) . CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3) .

1048

P06731

NP_004354

Human, Rat

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

CEACAM5 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1462 - Rat Lung Tissue Lysate

1 mg/mL

CEACAM5 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CEACAM5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

CEACAM5 antibody is human, mouse and rat reactive. CEACAM5 antibody is predicted to not cross-react with other CEACAM protein family members.

CEACAM5

Cat. No. 10-101 - Human Lung Tissue Slide

Carcinoembryonic antigen-related cell adhesion molecule 5

Homo sapiens

Gold P and Freedman SO. Specific carinoembryonic antigens of the human digestive system. J. Exp. Med. 1965; 122:467-81.

Kuespert K, Pils S, and Hauck CR. CEACAMs: their role in physiology and pathophysiology. Curr. Opin. Cell Biol. 2006; 565-71.

Yoshioka T, Masuko T, Kotanagi H, et al. Homotypic adhesion though carcinoembryonic antigen plays a role in hepatic metastasis development. Jpn. J. Cancer Res. 1998; 89:177-85.

CEACAM5 Antibody : CEA, CD66e, CEA, Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen

ELISA, WB

98986445

Liquid