Cediranib (AZD2171)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
288383-20-0
NSC-732208
C16060-10mg
VEGFR
Protein Tyrosine Kinase
CC1=CC2=C (N1) C=CC (=C2F) OC3=NC=NC4=CC (=C (C=C43) OC) OCCCN5CCCC5
C25H27FN4O3
Cediranib (AZD2171, NSC-732208) is a highly potent VEGFR (KDR) inhibitor with IC50 of <1 nM, also inhibits Flt1/4 with IC50 of 5 nM/≤3 nM, similar activity against c-Kit and PDGFRβ, 36-, 110-fold and >1000-fold selective more for VEGFR than PDGFR-α, CSF-1R and Flt3 in HUVEC cells. Cediranib (AZD2171) induces autophagic vacuole accumulation. Phase 3.
2 years -80 in solvent
Beschrijving
Cediranib (AZD2171) Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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