CEL Antilichaam - C - terminale regio : Biotine (ARP33857 P050-Biotine)

Carboxyl ester lipase (bile salt-stimulated lipase)

BAL, FAP, BSDL, BSSL, CELL, FAPP, LIPA, CEase, MODY8

1056

P19835

NP_001798

Human, Mouse, Rat, Horse, Pig

The immunogen is a synthetic peptide directed towards the C - terminal region of human CEL

CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

OLR1; BPGM; LTF

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Horse: 77%; Human: 100%; Mouse: 77%; Pig: 85%; Rat: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

80kDa

Strausberg, R.L., (2007) J. Clin. Invest. 117 (12), 3708-3719

Wet Ice

756

CEL

CEL

Rabbit

Bile salt-activated lipase

NM_001807

VTPTGDSETAPVPPTGDSGAPPVPPTGDSEAAPVPPTDDSKEAQMPAVIR