Cellulaire apoptose Gevoeligheid (CSE1L) Mouse Monoclonal Antibody [Kloon ID: LBI4G1]

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]

Carrier-free (BSA/glycerol-free) CSE1L mouse monoclonal antibody, clone LBI4G1

CAS; CSE1; XPO2

Homo sapiens chromosome segregation 1 like (CSE1L), transcript variant 1, mRNA.

1434

P55060

Unconjugated

WB 1:500, IHC 1:2000

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CSE1L

https://www.ncbi.nlm.nih.gov/gene/?term=1434

https://www.uniprot.org/uniprot/P55060