CEP290 Antilichaam

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

80184

O15078

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 950-1050 of human CEP290 (NP_079390.3) .

Unconjugated

Primary Antibodies

Cell Cycle, Neuroscience

Affinity purification

U-87MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 290kDa

IgG

WB: 1:500 - 1:2000

CEP290

DU145

Centrosomal protein 290kDa

Homo sapiens

CEP290, prostate cancer antigen T21, nephrocytsin-6, monoclonal 3H11 antigen, CTCL tumor antigen se2-2, 3H11Ag, BBS14, FLJ13615, FLJ21979, JBTS5, JBTS6, KIAA0373, LCA10, MKS4, NPHP6, SLSN6, rd16, centrosomal protein 290 kDa, CEP290

WB

Liquid