CEP290 Polyklonale Antilichaam, APC-Cy7 Vervoeging

This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer. [provided by RefSeq, Jul 2008

3H11AG; Bardet-Biedl syndrome 14 protein; BBS14; Cancer/testis antigen 87; CE290_HUMAN; Centrosomal protein 290kDa; Centrosomal protein of 290 kDa; Cep290; CT87; CTCL tumor antigen se2 2; FLJ13615; FLJ21979; JBTS5; JBTS6; KIAA0373; LCA10; Meckel syndrome, type 4; MKS4; Monoclonal; 3H11 antigen; Nephrocystin 6; Nephrocystin-6; NPHP6; POC3; POC3 centriolar protein homolog; Prostate cancer antigen T21; rd16; SLSN6 1, 2, 5; SLSN6; Tumor antigen se2-2.

80184

O15078

Cytoplasm

Mouse

131-230/2479

CEP290

APC-Cy7

KLH conjugated synthetic peptide derived from human CEP290

IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

650nm/780nm

1µg/µl

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

80184

Human, Rat, Dog, Cow, Sheep, Horse