CFS-9

FGF-9 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express the FGFR 1c, 2c, 3b, 3c, and 4. Recombinant human FGF-9 is a 23.2 kDa protein consisting of 206 amino acid residues.

FGF9; GAF; SYNS3; HBFG-9

2254

P31371

NP_002001.1

NM_002010

13q11-q12

Human

Human, Mouse

PLGEVGNYFG VQDAVPFGNV PVLPVDSPVL LSDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS

< 0.1 ng/µg of protein (< 1EU/µg)

> 95% by SDS-PAGE & HPLC analyses

Determined by its ability to stimulate the proliferation of mouse balb/c 3T3 cells using a concentration range of 1.0-5.0 ng/ml.

206

Lyophilized

23.2 kDa

E. coli