CFTR-antilichaam

The cystic fibrosis transmembrane conductance regulator (CFTR) protein is a member of the ATP-binding cassette (ABC) transporter superfamily, and a member of the MRP subfamily that is involved in multi-drug resistance (1,2) . CFTR functions as a chloride channel and controls the regulation of other transport pathways (3) . Mutations in this gene are associated with the autosomal recessive disorder cystic fibrosis, the most common, fatal, inherited disease of caucasian populations (1) .

1080

P13569

NP_000483

Human, Mouse, Rat

Unconjugated

Primary Antibodies

Signal Transduction

CFTR antibody is affinity chromatography purified via peptide column.

Cat. No. 1308 - Human Small Intestine Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Sheep: (100%), Rabbit: (100%), Bovine: (95%), Pig: (89%), Horse: (89%), Guinea pig: (89%)

CFTR Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

CFTR antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.

IgG

CFTR antibody is human, mouse and rat reactive.

CFTR

Cat. No. 11-801 - Human Small Intestine Tissue Slide

Cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)

Homo sapiens

Kerem B, Rommens JM, Buchanan JA, et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989; 245:1073-80.

Harris A and Argent BE. The cystic fibrosis gene and its product CFTR. Semin. Cell Biol. 1993; 4:37-44.

Schwiebert EM, Benos DJ, Egan ME, et al. CFTR is a conductance regulator as well as a chloride channel. Physiol. Rev. 1999; 79:S145-66.

CFTR Antibody: CF, MRP7, ABC35, ABCC7, CFTR/MRP, TNR-CFTR, dJ760C5.1, Cystic fibrosis transmembrane conductance regulator, ATP-binding cassette sub-family C member 7, CFTR

ELISA, WB, IHC-P, IF

90421313

Liquid