CHFR Antilichaam

This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.

55743

Q96EP1

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human CHFR (NP_001154818.1) .

Unconjugated

Primary Antibodies

Cancer, Cell Cycle

Affinity purification

HT-1080

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 70kDa

IgG

WB: 1:500 - 1:2000

CHFR

22Rv1

HepG2

Mouse kidney

Mouse testis

Checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase

Homo sapiens

CHFR, FLJ10796, FLJ33629, RNF116, RNF196

WB

Liquid