
CHIR-99021 (Laduviglusib)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
252917-06-9
CT99021
C16218-10mM/1mL
GSK-3
PI3K/Akt/mTOR
CC1=CN=C (N1) C2=CN=C (N=C2C3=C (C=C (C=C3) Cl) Cl) NCCNC4=NC=C (C=C4) C#N
C22H18Cl2N8
Laduviglusib (CHIR-99021, CT99021) is a GSK-3α and GSK-3β inhibitor with IC50 of 10 nM and 6.7 nM, respectively. CHIR99201 does not exhibit cross-reactivity against cyclin-dependent kinases (CDKs) and shows a 350-fold selectivity toward GSK-3β compared to CDKs. CHIR99021 functions as a Wnt/β-catenin activator and induces autophagy.
2 years -80 in solvent
Beschrijving
CHIR-99021 (Laduviglusib) Beschikbaar in 10 mM / 1 mL. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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