Chloor[N,N'-disalicylideen-1,2-diamino]ijzer (III)
Gecertificeerd

Chloor[N,N'-disalicylideen-1,2-diamino]ijzer (III)

Catalog #: HY-W698255-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

Chlorido[N, N'-disalicylidene-1,2-phenylenediamine]iron (III) generates lipid-based ROS and induce ferroptosis

CAS Number

39916-28-4

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ferroptosis; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Cancer

Smiles

[Cl-][Fe+3]123[O-]C4=C(C=[N]1C5=C([N]2=CC6=C([O-]3)C=CC=C6)C=CC=C5)C=CC=C4

Molecular Formula

C20H14ClFeN2O2

Molecular Weight

405.64

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Jessica Sagasser, et al. A New Approach in Cancer Treatment: Discovery of Chlorido[ N, N'-disalicylidene-1,2-phenylenediamine]iron (III) Complexes as Ferroptosis Inducers. J Med Chem. 2019 Sep 12;62 (17) :8053-8061.|[2]Soo-Young Lee, et al. [FeIII (salophene) Cl], a potent iron salophene complex overcomes multiple drug resistance in lymphoma and leukemia cells. Leukemia Research 35 (2011) 387-393.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W698255/

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Beschrijving

Chlorido[N, N'-disalicylidene-1,2-phenylenediamine]iron (III) generates lipid-based ROS and induce ferroptosis

Specificaties

ProductnaamChloor[N,N'-disalicylideen-1,2-diamino]ijzer (III)
Categorie
Beschikbare grootte5 mg
CatalogusnummerHY-W698255-01