CHMP2B Antilichaam

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration.

25978

Q9UQN3

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 1-213 of human CHMP2B (NP_054762.2) .

Unconjugated

Primary Antibodies

Autophagy, Cell Cycle, Neuroscience, Signal Transduction

Affinity purification

MCF7

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 28kDa

IgG

CHMP2B

BT-474

Lovo

Mouse kidney

Charged multivesicular body protein 2B

Homo sapiens

ALS17, CHMP2.5, DMT1, VPS2-2, VPS2B, charged multivesicular body protein 2b, VPS2 homolog B, chromatin modifying protein 2B, vacuolar protein-sorting-associated protein 2-2

WB, IHC, IF

Liquid