Cholzuur-3-sulfaat

Cholic acid 3-sulfate is the sulfated metabolite of Cholic acid , produced by liver enzyme sulfotransferase-2A1. Cholic acid 3-sulfate is less toxic than the parent compound, thus serving as a detoxification pathway for bile acids. Cholic acid 3-sulfate does not have the effect of stimulating intestinal secretion[1].

66167-89-3

12352211

Drug Metabolite

Metabolic Enzyme/Protease

Metabolism-protein/nucleotide metabolism

Metabolic Disease

O[C@H]1[C@@]2([H])[C@@]3([H])[C@@]([C@@](CC3)([H])[C@H](C)CCC(O)=O)([C@H](C[C@]2([H])[C@@]4([C@](C[C@@H](CC4)OS(=O)(O)=O)([H])C1)C)O)C

C24H40O8S

488.63

[1]Hofmann AF, et al. Altered bile acid metabolism in childhood functional constipation: inactivation of secretory bile acids by sulfation in a subset of patients. J Pediatr Gastroenterol Nutr. 2008 Nov;47 (5) :598-606.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N17272/

Natural Products

No Development Reported