CHRM2 Antilichaam

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

1129

P08172

Human, Mouse

Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human CHRM2 (NP_001006629.1) .

Unconjugated

Primary Antibodies

Neuroscience, Signal Transduction

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 52kDa

IgG

CHRM2

HepG2

Cholinergic receptor, muscarinic 2

Homo sapiens

7TM receptor, cholinergic receptor, muscarinic 2, CHRM2, FLJ43243, HM2, MGC120006, MGC120007, muscarinic acetylcholine receptor M2, muscarinic M2 receptor, OTTHUMP00000208393, OTTHUMP00000208394, OTTHUMP00000208395, OTTHUMP00000208396

WB, IF

Liquid