CHRNA3 Antilichaam

This locus encodes a member of the nicotinic acetylcholine receptor family of proteins. Members of this family of proteins form pentameric complexes comprised of both alpha and beta subunits. This locus encodes an alpha-type subunit, as it contains characteristic adjacent cysteine residues. The encoded protein is a ligand-gated ion channel that likely plays a role in neurotransmission. Polymorphisms in this gene have been associated with an increased risk of smoking initiation and an increased susceptibility to lung cancer. Alternatively spliced transcript variants have been described.

1136

P32297

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 32-240 of human CHRNA3 (NP_000734.2) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 57kDa

IgG

WB: 1:500 - 1:2000

CHRNA3

HepG2

Mouse brain

Rat liver

Cholinergic receptor, nicotinic, alpha 3 (neuronal)

Homo sapiens

CHRNA3, LNCR2, PAOD2, NACHRA3

WB

Liquid