CHRNE Antilichaam

Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

1145

Q04844

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 21-239 of human CHRNE (NP_000071.1) .

Unconjugated

Primary Antibodies

Neuroscience

Affinity purification

HepG2

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 45kDa

IgG

WB: 1:1000 - 1:4000

CHRNE

Mouse skeletal muscle

Rat kidney

Rat skeletal muscle

Cholinergic receptor, nicotinic, epsilon (muscle)

Homo sapiens

CHRNE, ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS

WB

Liquid