CHST8 (NM 022467) Humaan Recombinant Proteïne

The protein encoded by this gene belongs to the sulfotransferase 2 family. It is predominantly expressed in the pituitary gland, and is localized to the golgi membrane. This protein catalyzes the transfer of sulfate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans. It is responsible for sulfation of GalNAc on luteinizing hormone (LH), which is required for production of the sex hormones. Mice lacking this enzyme, exhibit increased levels of circulating LH, and precocious sexual maturation of both male and female mice. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

Purified recombinant protein of Human carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 (CHST8), transcript variant 3, Asp33-Val282, with N-terminal His tag, expressed in E. coli, 50ug

GalNAc4ST; GALNAC4ST1; PSS3

64377

Q9H2A9

NM_022467

19q13.11

E. coli

N-His

>50 ug/mL as determined by microplate BCA method

> 80% as determined by SDS-PAGE and Coomassie blue staining

Liquid

50mM Tris, 8M Urea, pH8.0

Transmembrane

28.5 kDa

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

CHST8

Human

NP_071912

https://www.ncbi.nlm.nih.gov/gene/64377

https://www.uniprot.org/uniprot/Q9H2A9

https://www.ncbi.nlm.nih.gov/nuccore/NM_022467

https://www.ncbi.nlm.nih.gov/nuccore/NP_071912