Cicletanine (hydrochloride)

Cicletanine hydrochloride is an orally active Furopyridine-derivative antihypertensive agent. Cicletanine hydrochloride stimulates NO release. Cicletanine hydrochloride induces effective pulmonary vasodilation[1][2].

82747-56-6

12352005

H315-H319

Drug Derivative; NO Synthase

Immunology/Inflammation; Others

Cardiovascular Disease

ClC1=CC=C(C2OCC3=C(C(C)=NC=C32)O)C=C1.Cl

C14H13Cl2NO2

298.16

P264-P280-P302+P352-P305+P351+P338-P362+P364

[1]Saadjian A, et al. Long-term effects of cicletanine on secondary pulmonary hypertension. J Cardiovasc Pharmacol. 1998 Mar;31 (3) :364-71.|[2]Kalinowski L, et al. Cicletanine stimulates nitric oxide release and scavenges superoxide in endothelial cells. J Cardiovasc Pharmacol. 2001 Jun;37 (6) :713-24.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W700616/

Reference compound2

No Development Reported