Cilofexor (GS-9674)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1418274-28-8
GS-9674
C11995-5mg
FXR
Metabolism
C1CC1C2=C (C (=NO2) C3=C (C=CC=C3Cl) Cl) COC4=CC (=C (C=C4) C5 (CN (C5) C6=NC=CC (=C6) C (=O) O) O) Cl
C28H22Cl3N3O5
Cilofexor (GS-9674) is a potent, selective oral agonist of farnesoid X receptor (FXR) with an EC50 of 43 nM. It has demonstrated anti-inflammatory, antifibrotic effects, and reduced portal pressure in preclinical liver fibrosis models, showing potential therapeutic benefit for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research.
Beschrijving
Cilofexor (GS-9674) Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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