CIR Antilichaam - C-terminal regio : HRP (ARP38523_P050-HRP)

Corepressor interacting with RBPJ, 1

CIR

9541

Q86X95

NP_004873

Human

The immunogen is a synthetic peptide directed towards the C terminal region of human CIR

CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC) . CIR is also required for RBPSUH-mediated repression of transcription.

CEP76; NEK6; U2AF1; SRSF2; SRSF1; RP9; HDAC2; SAP30; SNW1; TCEA1; NCOR2; RBPJ

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

52kDa

Maita, H., (2005) Exp. Cell Res. 303 (2), 375-387

Wet Ice

450

CIR1

CIR1

Rabbit

Corepressor interacting with RBPJ 1

NM_004882

RSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLYRGEKMYREHPG