Cis-5-dodeceenzuur (standaard)

Cis-5-Dodecenoic acid (Standard) is the analytical standard of cis-5-Dodecenoic acid. This product is intended for research and analytical applications. cis-5-Dodecenoic acid is an inhibitor of COX-I and COX-II with anti-inflammatory activity. cis-5-Dodecenoic acid reduces prostaglandin synthesis by inhibiting COX enzyme activity and is involved in the fatty acid -β oxidative metabolic pathway. The metabolic rate of cis-5-Dodecenoic acid is significantly lower than that of saturated fatty acids. cis-5-Dodecenoic acid can be used in the research of anti-inflammation, fatty acid metabolism mechanisms and related physiological and pathological processes[1][2].

2430-94-6

12352211

COX; Reference Standards

Immunology/Inflammation; Others

Inflammation/Immunology

CCCCCC/C=C\CCCC(O)=O

C12H22O2

198.30

[1]Henry GE, et al. Antioxidant and cyclooxygenase activities of fatty acids found in food. J Agric Food Chem. 2002 Apr 10;50 (8) :2231-4.|[2]Tserng KY, et al. Comparison of metabolic fluxes of cis-5-enoyl-CoA and saturated acyl-CoA through the beta-oxidation pathway. Biochem J. 1995 Apr 1;307 (Pt 1) (Pt 1) :23-8

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N8469R/

Reference Standards

COX-1; COX-2