CK-1alfa (fo Tyr294) Antilichaam

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.

1452;122011

P48729; Q8N752

NP_001883.4

Human, Mouse, Rat

CK-1alpha (phospho Tyr294) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 294 (Y-D-Y (p) -T-F) derived from Human CK-1alpha.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

37 kDa

IgG

The antibody detects endogenous levels of CK-1alpha only when phosphorylated at tyrosine 294.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

CSNK1A1, CSNK1A1L

Casein kinase 1, alpha 1, casein kinase 1, alpha 1-like

Homo sapiens

Tapia C., FEBS Lett. 349:307-312 (1994) .

Fish K.J., J. Biol. Chem. 270:14875-14883 (1995) .

Halleck A., Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.

KC1A, CKI-alpha, CSNK1A1, alpha isoform, Casein kinase I

WB, IHC

68303575

Liquid