CK1 Antilichaam [3C10F7 / 3C10G5 / PMC01 / 4D12B3]

CK1 (also designated Cytokeratin 1 or KRT1), with 644-amino acid protein (about 70 kDa), is a member of the keratin family. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells.CK1 consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. CK1 is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma.

1452

P48729

P48729

Human

Ni-NTA purified truncated recombinant CK1 expressed in E. Coli strain BL21 (DE3) .

3C10F7 / 3C10G5 / PMC01 / 4D12B3

Unconjugated

Primary Antibodies

Other

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

CK1 monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

CSNK1A1

Casein kinase 1, alpha 1

Homo sapiens

Ricardo G. Espinola, Robin A. Pixley, Berhane Ghebrehiwet. Blood (ASH Annual Meeting Abstracts), Nov 2005; 106: 2666.

CK1, CKI-alpha, CK1a, CKIa, HLCDGP1, PRO2975, HEL-S-77p

ELISA, WB, IHC

31077177