CK3-peptide

CK3 peptide is an NRP-1 targeting peptide with the amino acid sequence CLKADKAKC. The CK3 peptide specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging show significant accumulation of CK3 peptide in xenograft tumors in nude mice. CK3 peptide can be used for molecular imaging studies of breast cancer.

1801552-75-9

12352209

Complement System

Immunology/Inflammation

Cancer-programmed cell death

Cancer

O=C([C@@H](N)CSSC[C@H](NC1=O)C(O)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CCCCN)=O)C)=O)CCCCN)=O)CC(O)=O)=O)C)=O)CCCCN)=O)CC(C)C

C40H72N12O12S2

977.20

[1]Feng GK, et al. SPECT and near-infrared fluorescence imaging of breast cancer with a neuropilin-1-targeting peptide. J Control Release. 2014 Oct 28;192:236-42.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P10788/

Peptides

No Development Reported