CKit Antilichaam [8D7B4 / 8D7D4 / 7H6B2 / 7H6B12]

C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor) . Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

3815

P10721

P10721

Human

Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3) .

8D7B4 / 8D7D4 / 7H6B2 / 7H6B12

Unconjugated

Primary Antibodies

Innate Immunity

Antibody is purified by protein A affinity chromatography.

Batch dependent

Ascitic fluid containing 0.03% sodium azide.

None

Blue Ice

C-Kit monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

KIT

V-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

Homo sapiens

Mojica WD et.alHistopathology. 2005 Nov;47 (5) :517-22.

Tong WD et.alInt J Colorectal Dis. 2005 Jul;20 (4) :363-7. Epub 2005 Feb 2.

Nakai Y et.alBiochem Biophys Res Commun. 2005 Nov 11;337 (1) :289-96.

SCFR, Piebald trait protein, SCFR, PBT, C-Kit, CD117

ELISA

125472