Claudin 16 Polyklonale Antilichaam, Biotinevervoeging

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in paracellular magnesium reabsorption. Required for a selective paracellular conductance. May form, alone or in partnership with other constituents, an intercellular pore permitting paracellular passage of magnesium and calcium ions down their electrochemical gradients. Alternatively, it could be a sensor of magnesium concentration that could alter paracellular permeability mediated by other factors.

HOMG3; PCLN1; Claudin-16; Paracellin-1; PCLN-1; CLDN16

10686

Q9Y5I7

Cell membrane

95-150/305

Claudin 16

Biotin

KLH conjugated synthetic peptide derived from human Claudin 16

ELISA, IHC-P, IHC-F

Purified by Protein A.

1µg/µl

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C for 12 months.

10686

Human, Mouse, Rat, Dog, Cow, Sheep, Chicken, Rabbit