Claudin 5 (fosfo-Tyr217) Antilichaam

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.

7122

O00501

NP_001124333.1

Human, Mouse, Rat

Claudin 5 (phospho Tyr217) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y (p) -V) derived from Human Claudin 5.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

23 kDa

IgG

The antibody detects endogenous levels of Claudin 5 only when phosphorylated at tyrosine 217.

CLDN5

Claudin 5

Homo sapiens

Sirotkin H., Genomics 42:245-251 (1997) .

Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11 (2004) .

The MGC Project Team; Genome Res. 14:2121-2127 (2004) .

CLD5, CLDN5, TMDVCF

IHC

6685271

Liquid