Claudin 6 (CLDN6) Mouse Monoclonal Antibody [Kloon ID: LBI2A3]

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. [provided by RefSeq, Aug 2010]

Carrier-free (BSA/glycerol-free) CLDN6 mouse monoclonal antibody, clone LBI2A3

Claudin 6; OTTHUMP00000159248

Homo sapiens claudin 6 (CLDN6), mRNA.

9074

P56747

Unconjugated

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction

WB 1:500

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Transmembrane

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

CLDN6

https://www.ncbi.nlm.nih.gov/gene/?term=9074

https://www.uniprot.org/uniprot/P56747