Claudin18.2 Monoklonale antilichamen

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-2) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

CLDN18

P56856

Human

Human Claudin18.2 mRNA

UNQ; PRO; CLDN; SFTA; Claudin; Claudin-; CLDN18; SFTA5; SFTPJ; Claudin-18; Claudin-18.2; UNQ778; PRO1572; SPJ

10C12

Unconjugated

WB; IHC-P

Signal Transduction

Protein A

1 mg/mL

WB 1:500-1:2000; IHC-P 1:500-1:2000

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/1rCkHRLQ

IgG2a