Clavariopsin B

Clavariopsin B is a cyclic depsipeptide antibiotic. Clavariopsin B shows antifungal activity for Candida albicans IFO 0583, Candida albicans ATCC 10231, Aspergillus niger AJ117374, Aspergillus fumigatus AJ117190, Aspergillus fumigatus JCM1739 with MIC values of 8, 8, 16, 4, 4 μg/mL, respectively[1].

227083-48-9

12352005

Antibiotic; Fungal

Anti-infection

Infection

O=C1N2[C@](CCCC2)([H])C(N[C@H](C(N[C@H](C(N([C@H](C(N([C@@](C(N([C@@](C(NCC(N([C@H](C(N[C@H](C(O[C@@H]1C(C)C)=O)CC3=CC=C(C=C3)OC)=O)C(C)C)C)=O)=O)([H])[C@@H](C)CC)C)=O)([H])[C@@H](C)CC)C)=O)CC(O)=O)C)=O)C(C)C)=O)C(C)C)=O

C58H93N9O14

1140.41

[1]Kaida K, et al. New cyclic depsipeptide antibiotics, clavariopsins A and B, produced by an aquatic hyphomycetes, Clavariopsis aquatica. 1. Taxonomy, fermentation, isolation, and biological properties. J Antibiot (Tokyo) . 2001 Jan;54 (1) :17-21.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14961/

Natural Products

No Development Reported