Clavicoronzuur

Clavicoronic acid is an avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptases inhibitor with Ki values of 130, 68 µM, respectively. Clavicoronic acid inhibits the multiplication of vesicular stomatitis virus by interfering with this virus's RNA-directed RNA-polymerase. Clavicoronic acid shows no cytotoxicity[1].

139748-98-4

12352211

DNA/RNA Synthesis

Cell Cycle/DNA Damage

Infection

CC1=C(C(C(O)=O)=O)C(C=O)=C[C@@]2([H])[C@]1([H])CC(C)(C)C2

C15H18O4

262.30

[1]Erkel G, et al. Antibiotics from basidiomycetes. XLI. Clavicoronic acid, a novel inhibitor of reverse transcriptases from Clavicorona pyxidata (Pers. ex Fr.) Doty. J Antibiot (Tokyo) . 1992 Jan;45 (1) :29-37.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N14957/

Natural Products

No Development Reported